This stock has shown some massive uptrends and changes in how these CV plays are panning out.
Most are doing the mass amount of movement PM with the setup being AH>

MESO in particular is up from $6 to mid 14's AH with a high of 20 from 16 in the first 5 minutes and the great dip buy opportunity.

This has volume not seen in years with the previous JAN spike from $8 to $11 having used only 250k, Friday's move had 17M in volume.

Personally, I wouldn't play this as a breakout as it is massively overextended on macro charts.
I would only touch this on a dip buy at the point as long as we have a nice spike in the morning.

Breakout buyers beware. This thing moves fast, if you aren't in at breakout don't chase.

On the other hand, this thing is hot news and could see a DRYS situation with shorts pumping the stock to crazy prices. Still, the safer play is a dip buy if you are comfortable with your Lv 2 eyes.